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Medchemexpress LLC 3-[[(3,4-dichlorophenyl)amino]carbonyl]-bicyclo[2.2.1]hept-5-ene-2-carboxylic acid | 199735-88-1 | >98.0% | 326.17 g/mol | C15H13Cl2NO3 | 25 MG
SDP

Supplier:  Medchemexpress LLC HY10799925MG

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CADD522 is a small-molecule inhibitor of RUNX family transcription factor 2 (RUNX2) DNA binding used for research in cancer biology. It inhibits RUNX2 binding in cell-free and cellular assays, downregulates RUNX2 target genes, reduces clonogenic survival in breast cancer cell lines, and has shown antitumor activity in mouse models. For research use only.

  • Inhibits RUNX2-DNA binding in cell-free and cellular assays.
  • Reduces expression of RUNX2 target genes such as MMP-13 and VEGF.
  • Decreases clonogenic survival in multiple breast cancer cell lines.
  • Demonstrated tumor volume reduction in mouse tumor models.
  • High purity suitable for biological studies (≥98%).
  • Recommended storage as a solid at -20°C; long-term in solvent at -80°C.

Catalog No. 50-002-42469


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