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Medchemexpress LLC 3-(3-(N-(2-chloro-3-trifluoromethylbenzyl)(2,2-diphenylethyl)amino)propoxy)phenylacetic acid | 405911-09-3 | 99.8% | 582.05 | C33H31ClF3NO3 | 10 MG
SDP

Supplier:  Medchemexpress LLC HY1062710MG

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GW3965 is a potent, selective liver X receptor (LXR) agonist used in research to activate human LXRα and LXRβ. It is employed to study cholesterol metabolism, ABCA1 regulation, platelet function, neurosteroid modulation, and effects in cellular and animal disease models.

  • Potent LXR agonist; EC50 190 nM (hLXRα) and 30 nM (hLXRβ).
  • Promotes ABCA1 expression and cholesterol efflux.
  • Active in cell and animal models, including effects on tumor growth and neurosteroid levels.
  • Supplied as a white to off-white solid with high purity (~99.8%).
  • Soluble in DMSO; in vivo formulations often use 10% DMSO in corn oil.
  • Store powder at -20°C for long-term stability; store solutions at -80°C for extended storage.

Catalog No. 50-002-44404


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