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Medchemexpress LLC 3'-Azido-3'-deoxy-5-methylcytidine | 1282040-14-5 | 99.9% | 282.26 | 1 ML
Supplier: Medchemexpress LLC HY11164010MM/1ML
3'-Azido-3'-deoxy-5-methylcytidine (CS-92) is a potent xenotropic murine leukemia-related retrovirus (XMRV) inhibitor with a CC50 of 43.5 μM in MCF-7 cells. It also inhibits HIV-1 reverse transcriptase with an EC50 of 0.06 μM in peripheral blood mononuclear (PBM) cells. This compound is a click chemistry reagent, containing an Azide group, and can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Inhibits HIV-1 at an EC50 of 0.06 μM in PBM cells
- Inhibits XMRV at a CC50 of 43.5 μM in MCF-7 cells
- Functions as a click chemistry reagent
- Contains an Azide group for CuAAc reactions with Alkyne groups
- Participates in SPAAC reactions with DBCO or BCN groups
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