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Apexbio Technology LLC Aztreonam 78110-38-0 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC A59315.1
Aztreonam (CAS 78110-38-0) is a synthetic monocyclic -lactam antibiotic targeting penicillin-binding protein 3 (PBP3) It is designed to bind to PBP3 thereby disrupting bacterial cell wall synthesis and inhibiting bacterial growth Aztreonam exerts its biological activity primarily through inhibition of cell wall synthesis in aerobic Gram-negative bacteria In in vitro studies Aztreonam demonstrates selective antibacterial activity with reported IC50 values ranging from 0 05 8 g/mL against sensitive Gram-negative bacterial strains depending on species and experimental conditions Based on these pharmacological properties Aztreonam holds research potential in studies of bacterial resistance mechanisms -lactamase susceptibility profiles and evaluation of antibiotic permeability
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