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Medchemexpress LLC 3-cyano-5-[[[2,4-dimethyl-5-[6-(3-pyridinyl)-1H-imidazo[1,2-b]pyrazol-1-yl]...phenyl]pentafluorosulfur | 1448316-08-2 | 99.3% | 558.53 g/mol | C26H19F5N6OS | 10 MG

Supplier: Medchemexpress LLC HY10075610MG
BAY-826 is a selective, potent small-molecule inhibitor of the TIE-2 (TEK) receptor tyrosine kinase used as a research chemical probe. It exhibits low-nanomolar binding (reported Kd ≈ 1.6 nM) and has been characterized in biochemical, cellular, and in vivo models. Supplied as a solid with high reported purity, it is intended for research use only.
- Low-nanomolar potency against TIE-2 enabling sensitive biochemical assays.
- High selectivity across kinases to reduce off-target activity.
- Validated in cellular assays for target engagement.
- Shown in vivo activity in preclinical models.
- High reported purity suitable for pharmacology studies.
- Soluble in DMSO for solution formulations.
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