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Apexbio Technology LLC 3-Deazaadenosine(Synonyms: 3-Deazaadenosine, 3-Deaza-adenosine, 3DA, Cordycepin analog, Tubercidin), 5mg, CAS: 6736-58-9.
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Supplier:  Apexbio Technology LLC B61215

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3-Deazaadenosine (CAS 6736-58-9) is an inhibitor of S-adenosylhomocysteine (SAH) hydrolase an enzyme responsible for the reversible hydrolysis of SAH into adenosine and homocysteine Inhibition of SAH hydrolase by 3-Deazaadenosine (Ki 3 9 M) elevates intracellular SAH concentrations altering the SAH-to-SAM (S-adenosylmethionine) ratio and consequently suppressing SAM-dependent methyltransferase activities In vitro studies demonstrate its antiviral activity against Ebola and Marburg viruses in various primate and mouse cell lines Animal studies indicate protective efficacy against lethal Ebola infection in BALB/c mice Currently 3-Deazaadenosine remains in preclinical research

Catalog No. 50-000-60469


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