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Selleck Chemical LLC 3PO 5mg 18550-98-6 3-(3-pyridinyl)-1-(4-pyridinyl)-2-propen-1-one
Supplier: Selleck Chemical LLC S76395MG
3PO (3-(3-pyridinyl)-1-(4-pyridinyl)-2-propen-1-one) is a small-molecule inhibitor of PFKFB3 with an IC50 of 22.9 ?M for recombinant human PFKFB3 protein and does not inhibit PFK-1 activity. It suppresses glucose uptake, and decreases the intracellular concentration of Fru-2,6-BP, lactate, ATP, NAD+, and NADH. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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