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Medchemexpress LLC (3S,4S)-PF-06459988 | 1858291-14-1 | 98.97% | 431.88 | 25 MG
Supplier: Medchemexpress LLC 25MGHY19985A
(3S,4S)-PF-06459988 is the S enantiomer of PF-06459988, exhibiting less activity. It acts as a potent, irreversible inhibitor of T790M mutant epidermal growth factor receptor (EGFR). This compound demonstrates excellent selectivity against EGFR wild-type, featuring a minimally reactive electrophile to reduce off-target labeling.
- Acts as an S enantiomer of PF-06459988
- Potent irreversible inhibitor of T790M mutant EGFR
- Excellent selectivity against EGFR wild-type
- Minimally reactive electrophile reduces off-target labeling
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