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ATCC 3T3 L1-MBX; Embryonic Fibroblast; Mouse (Mus musculus)
Supplier: ATCC CRL3242

3T3-L1 MBX is a fibroblast cell line clone that was dervied from 3T3-L1 (ATCC CL-173) which was isolated from a mouse embryo. 3T3 L1-MBX clone was derived to ensure close to 100% differentiation to adipocytes and great response to insulin. In addition, 3T3 L1-MBX has a great insulin-stimulated glucose uptake response which is about 8-10 fold window with sub-maximal insulin concentration in 2-deoxyglucose uptake assay (2-DOG). This cell line would be a valuable tool for researchers who are interested in diabetes and obesity research areas This cell line was deposited by CymaBay Therapeutics (formerly Metabolex, Inc.) & Choi Y.
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