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Medchemexpress LLC 4-((21S,24S)-1-(bicyclo[6.1.0]non-4-yn-9-yl)-21-isopropyl-3,19,22-trioxo-24-(3-ureidopropyl)) | 2762519-08-2 | MFCD32062688 | 98.8% | 1546.93 g·mol⁻¹ | C80H127N11O19 | 1 MG
SDP

Supplier:  Medchemexpress LLC HY1411551MG

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endo-BCN-PEG4-Val-Cit-PAB-MMAE is a cleavable antibody-drug conjugate (ADC) linker containing an endo-bicyclononyne (BCN) click handle and a PEG4 spacer conjugated to monomethyl auristatin E (MMAE). It is used for ADC synthesis and for bioconjugation via strain-promoted alkyne-azide cycloaddition (SPAAC).

  • Cleavable Val-Cit-PAB linker for enzymatic release of payload.
  • Contains a PEG4 spacer to improve solubility and linker flexibility.
  • Endo-BCN group enables copper-free click conjugation to azide-bearing molecules.
  • Conjugated to MMAE for use in antibody-drug conjugate research.
  • Supplied in small milligram quantities for research and synthesis workflows.

Catalog No. 50-002-03931


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