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Medchemexpress LLC 4-[[4-(2-butynyloxy)phenyl]sulfonyl]-N-hydroxy-2,2-dimethyl-(3S)thiomorpholinecarboxamide | 287403-39-8 | 99.6% | 398.50 g/mol | C17H22N2O5S2 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY10144850MG

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TMI-1 (WAY-171318) is a small-molecule research tool that potently inhibits TNF-α converting enzyme (TACE/ADAM17) and multiple matrix metalloproteinases, induces apoptosis via caspase-dependent pathways, and has demonstrated activity in cell-based assays and animal models of inflammation and cancer.

  • Potent TACE inhibition (reported IC50 ≈ 8.4 nM)
  • Induces apoptosis in cancer cell lines via caspase-dependent mechanisms
  • Reduces TNF-α secretion and alleviates inflammatory symptoms in animal models
  • Available as solid and solution forms for in vitro and in vivo use
  • High purity suitable for research applications

Catalog No. 50-002-45422


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