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Medchemexpress LLC 4',5-Dihydroxyflavone | 6665-67-4 | 254.24 | 25 MG
Supplier: Medchemexpress LLC 25MGHYN1881
4',5-Dihydroxyflavone (Compound 2c; Compound B3) is a flavonoid compound. It can inhibit various oxidases, with IC50 values of less than 1 μM for collagenase A (ColA) and 66 μM for α-glucosidase. Its Ki value for soybean lipoxygenase-1 (LOX-1) is 102.6 μM. This compound is suitable for studies on anti-toxicity and anti-diabetes. 4',5-Dihydroxyflavone is also a potent inhibitor of ColA, a bacterial virulence factor that aids bacterial spread by degrading host collagen proteins.
- Type of flavonoid compound.
- Inhibits various oxidases.
- IC50 values for collagenase A (ColA) and α-glucosidase are < 1 μM and 66 μM, respectively.
- Ki value for soybean lipoxygenase-1 (LOX-1) is 102.6 μM.
- Can be used in studies on anti-toxicity and anti-diabetes.
- Potent inhibitor of ColA, a bacterial virulence factor.
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