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Medchemexpress LLC 4,6(1H,5H)-Pyrimidinedione, 1-(3-chloro-4-methylphenyl)-5-[3-(2-furanyl)-2-propen-1-ylidene] | 593273-05-3 | 99.2% | 372.83 | 25 MG
SDP

Supplier:  Medchemexpress LLC 25MGHY139108

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DCH36_06 is a potent and selective p300/CBP inhibitor. It mediates p300/CBP inhibition, leading to hypoacetylation on H3K18 in leukemic cells, and exhibits anti-tumor activity.

  • Potent and selective p300/CBP inhibitor.
  • Induces apoptosis in leukemic cells.
  • Arrests cell cycle at G1 phase.
  • Shows potent antiproliferative activity against a range of leukemia cell lines.
  • Blocks leukemic xenograft growth in mice.

Catalog No. 50-003-50643


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