Medchemexpress LLC 4-[6-[[4-(cyclopropylmethyl)piperazin-1-yl]methyl]-2-(5-fluoro-1H-indol-4-yl)thieno[3,2-d]pyrimidin | 955977-50-1 | 99.0% | 25 MG

Supplier:  Medchemexpress LLC HY1223525MG

PI-3065 is a selective small-molecule inhibitor of PI3K p110δ used as a research tool for biochemical and cellular studies. It displays low-nanomolar potency against p110δ and substantially reduced activity against other class I PI3K isoforms.

• Selective p110δ inhibitor (IC50 = 5 nM; Ki = 1.5 nM).
• Reduced activity against p110α (IC50 910 nM), p110β (IC50 600 nM), and p110γ (IC50 >10,000 nM).
• Molecular formula C27H31FN6OS and molecular weight 506.64 g/mol.
• High reported purity (~98.97%).
• Soluble in DMSO (25 mg/mL; 49.34 mM).
• Store powder at -20°C for long-term storage or 4°C for short-term storage.
• Intended for research use in biochemical assays and cell-based PI3Kδ signaling studies.

Catalog No. 50-002-31469