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Cayman Chemical 4-hydroxy Nonal-d3 500ug
SDP

Supplier:  Cayman Chemical 332101500 UG

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A non-steroidal mineralocorticoid receptor antagonist (Ki 0.104 UM for the human receptor) selective for mineralocorticoid receptors over ERa and ERB and glucocorticoid progesterone and androgen receptors (IC50s 100 UM for all) increases the urinary ratio of sodium to potassium in adrenalectomized rats inhibits aldosterone- and nephrectomy-induced increases in systolic blood pressure and urinary albumin levels as well as myocardial necrosis and fibrosis cardiac arterial degeneration and renal tubule damage in a rat model of renal hypertension at 3 or 10 mg/kg per day

Catalog No. 50-295-0357


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