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Medchemexpress LLC 4-hydroxymethylpyrazole | 25222-43-9 | 99.7% | 98.11 | 10 G
Supplier: Medchemexpress LLC HY3391410G
4-Hydroxymethylpyrazole is the primary metabolite of Fomepizole produced through hepatic oxidative metabolism. It exhibits a plasma concentration positively correlated with the administered dosage of Fomepizole and has a relatively short half-life. It also demonstrates inhibitory effects on alcohol dehydrogenase (ADH) in both humans and monkeys, though its inhibition constant is significantly higher than Fomepizole, making its in vivo impact negligible.
- Primary metabolite of Fomepizole
- Exhibits plasma concentration positively correlated with Fomepizole dosage
- Relatively short half-life
- Demonstrates inhibitory effects on alcohol dehydrogenase (ADH)
- For research use only
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