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Medchemexpress LLC 4-Hydroxymethylpyrazole | 25222-43-9 | 99.7% | 98.11 | 5 G
Supplier: Medchemexpress LLC HY339145G
4-Hydroxymethylpyrazole is the primary metabolite of Fomepizole, produced through hepatic oxidative metabolism. It has a plasma concentration positively correlated with the administered dosage of Fomepizole and a relatively short half-life. It inhibits alcohol dehydrogenase (ADH) in humans and monkeys, but its inhibition constant is significantly higher than Fomepizole's, rendering its in vivo impact negligible.
- Primary metabolite of Fomepizole
- Produced through hepatic oxidative metabolism
- Plasma concentration positively correlated with administered dosage
- Relatively short half-life
- Inhibits alcohol dehydrogenase (ADH) in humans and monkeys
- In vivo impact negligible
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