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Cayman Chemical 4-MethylumbelIferon 50g
Supplier: Cayman Chemical 2960350 G
A synthetic coumarin with diverse biological activities; inhibits hyaluronic acid synthesis in PC3-ML and DU145 cells (IC50s = ~0.4 mM for both); inhibits the growth of PC3-ML, DU145, C4-2B, LNCaP, and LAPC-4 prostate cancer cells (IC50s = 0.2-0.4 mM) and invasion and chemotactic motility of PC3-ML and DU145 cells in vitro; reduces tumor growth and microvessel density in a PC3-ML mouse xenograft model at 225 and 450 mg/kg twice per day; active against H. pylori and V. cholerae in vitro (MICs = 59 and 100-200 μg/ml, respectively); ex/em = 320 and 360 nm at low and high pH, respectively/455 and 445 nm at low and high pH, respectively.
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