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Medchemexpress LLC 4-Piperidinecarboxamide, 1-acetyl-N-[3-[4-[[4-(aminocarbonyl)phenyl]methyl]-1-piperidinyl] propyl]-N-(3-chloro-4-methylphenyl)- | 333994-00-6 | 99.95% | 553.14 | 1 ML
SDP

Supplier:  Medchemexpress LLC HY1997410MM/1ML

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TAK-220 is a selective and orally bioavailable CCR5 antagonist. It shows potent inhibitory activity against R5 isolates and does not affect binding to CCR1, CCR2b, CCR3, CCR4, or CCR7. It also selectively inhibits HIV-1 and shows no toxicity in uninfected PBMCs at concentrations greater than 100 nM.

  • Selective and orally bioavailable
  • Inhibits CCR5-mediated Ca2+ signaling
  • Potent inhibitory activity against R5 isolates
  • No toxicity in uninfected PBMCs at concentrations greater than 100 nM

Catalog No. 50-004-04963


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