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Medchemexpress LLC 4-tert-Octylphenol | 140-66-9 | 99.7% | 1000 G
Supplier: Medchemexpress LLC HYB19411000G
4-tert-Octylphenol is an endocrine-disrupting chemical and an estrogenic agent, also a biodegradation product of non-ionic surfactants alkylphenol polyethoxylates. It induces apoptosis in neuronal progenitor cells in offspring mouse brain, reduces bromodeoxyuridine (BrdU), mitotic marker Ki67, and phospho-histone H3 (p-Histone-H3), which leads to a reduction of neuronal progenitor proliferation. 4-tert-Octylphenol disrupts brain development and behavior in mice.
- Endocrine-disrupting chemical
- Estrogenic agent
- Biodegradation product of non-ionic surfactants alkylphenol polyethoxylates
- Induces apoptosis in neuronal progenitor cells in offspring mouse brain
- Reduces neuronal progenitor proliferation by affecting BrdU, Ki67, and phospho-histone H3
- Disrupts brain development and behavior in mice
- Promising for research of immune response, neuro-related diseases and ethology
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