Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000286410

Medchemexpress LLC (4R)-1-{[4,4-difluoro-1-(4-methoxyphenyl)cyclohexyl]carbonyl}-4-fluoro-N-1H-pyrazolo[4,3-b]pyridin-5-yl-d-prol... | 2259641-46-6 | 99.8% | 501.5 g·mol-1 | C25H26F3N5O3 | 10 MG
SDP

Supplier:  Medchemexpress LLC HY15224110MG

Encompass_Preferred

DS-9300 is a small-molecule, orally active, selective inhibitor of the EP300/CBP histone acetyltransferase (HAT) with a reported biochemical IC50 of 28 nM. Described in the Journal of Medicinal Chemistry and developed by Daiichi Sankyo, the compound has shown anticancer activity in preclinical prostate cancer models.

  • Potent EP300/CBP HAT inhibition (IC50 = 28 nM).
  • Orally active with demonstrated antitumor effects in preclinical prostate cancer models.
  • Selective activity for EP300/CBP over other HATs reported in the discovery study.
  • Provided as small-scale research quantities with analytical documentation available.
  • High reported purity (99.83%) and molecular formula C25H26F3N5O3.
  • Molecular weight approximately 501.5 g·mol-1.

Catalog No. 50-002-86410


May include imposed supplier surcharges.
Add to Cart

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.