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ATCC 4T1.2; Breast Carcinoma; Mouse (Mus musculus)

Supplier:  ATCC CRL3406

Encompass

4T1.2 is a cell line with epithelial-like morphology that was isolated in 1998 from the breast of a Balb/cfC3H mouse, mimicking Stage IV breast cancer in patients. Identified as a single cell clone of 4T1 (ATCC CRL-2539) with high propensity to metastasize spontaneously to bone, causing fractures and/or hind limb paralysis. Primary tumor growth properties similar to those of 4T1. It has applications for cancer research and is used for analysis of genes that regulate metastasis of breast cancer and/or drugs that might reduce spontaneous metastasis in immune competent Balb/c mice.

Catalog No. 50-238-4016


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