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Medchemexpress LLC 5-(4-Hydroxyphenyl)-3H-1,2-dithiole-3-thione | 18274-81-2 | 98.6% | 226.35 | 1 MG
Supplier: Medchemexpress LLC HY10958210MG
ADT-OH is a hydrogen sulfide-releasing donor that induces apoptosis and upregulates FADD, inhibiting FAK/Paxillin pathways. This compound shows potential for cancer research, demonstrating significant anti-metastatic activity in cellular studies on TNBC cells and in various mouse models, with limited effect on primary tumor growth.
- Induces apoptosis and upregulates FADD
- Inhibits FAK/Paxillin signaling pathways
- Shows anti-metastatic activity on malignant melanoma cells
- Enhances antitumor activity of celecoxib in colorectal cancer cells
- Promotes self-renewal and antiapoptosis ability of cultured NPCs
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