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Medchemexpress LLC 5-Aminosalicylic acid | 89-57-6 | C7H7NO3 | 1 MG
Supplier: Medchemexpress LLC HY15027S11MG
5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist, inhibiting p21-activated kinase 1 (PAK1) and NF-κB. It can also inhibit the activity of osteopontin (OPN).
- Specific PPARγ agonist
- Inhibits p21-activated kinase 1 (PAK1) and NF-κB
- Inhibits the activity of osteopontin (OPN)
- Demonstrates antineoplastic effect in xenograft tumor models
- Inhibits growth of HT-29 colon carcinoma cells in vitro
- Shows more potent inhibition of HT-29 cell proliferation when combined with Nimesulide
- Antitumorigenic effect is partially dependent on PPARγ
- Purity of 99.97%
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