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Medchemexpress LLC 5-aminosalicylic acid (mesalamine) | 89-57-6 | C7H7NO3 | 5 G
Supplier: Medchemexpress LLC HY150275G
5-Aminosalicylic Acid (Mesalamine) is a specific PPARγ agonist that also inhibits p21-activated kinase 1 (PAK1), NF-κB, and osteopontin (OPN) activity. This compound has demonstrated antineoplastic effects in xenograft tumor models, significantly reducing tumor weight and volume.
- Acts as a specific PPARγ agonist.
- Inhibits p21-activated kinase 1 (PAK1) and NF-κB.
- Inhibits osteopontin (OPN) activity.
- Induces degradation of p65 protein.
- Blocks NF-κB in intestinal epithelial cells (IECs) through PAK1 inhibition.
- Shows antineoplastic effects in xenograft tumor models.
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