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Medchemexpress LLC 5-cyclopropyl-2-[1-[(2-fluorophenyl)methyl]pyrazolo[5,4-b]pyridin-3-yl]pyrimidin-4-amine | 256376-24-6 | MFCD06411391 | 99.6% | 360.39 g/mol | C20H17FN6 | 25MG
SDP

Supplier:  Medchemexpress LLC HY1237625MG

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This compound is an orally active soluble guanylate cyclase (sGC) activator used in research to increase intracellular cyclic GMP (cGMP) and probe NO-independent sGC signaling. It is supplied as a white to off-white solid suitable for in vitro and in vivo studies, with recommended solubility and storage conditions for reproducible handling.

  • Purity 99.6%.
  • Molecular formula C20H17FN6; molecular weight 360.4 g/mol.
  • Solid form (white to off-white) for powder handling and storage.
  • Soluble in DMSO (17.5 mg/mL) for in vitro applications.
  • In vivo formulation options include 10% DMSO/40% PEG300/5% Tween-80/45% saline and other vehicles.
  • Recommended in vitro concentration 10 μM to increase cGMP in A7r5 cells.
  • Storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (2 years) or -20°C (1 year).

Catalog No. 50-002-37613


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