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Eurofins Discoverx Ready-to-Assay 5-HT6 Serotonin Receptor Frozen Cells, 2 Vials of Cells. (HTS111RTA)

Supplier:  Eurofins Discoverx HTS111RTA

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The Ready-to-Assay 5-HT6 Serotonin Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. serotonin/5-HT) based activation of HTR6 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses HTR6 alongside exogenous levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of HTR6, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.

Catalog No. 50-200-5902


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