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Medchemexpress LLC 5'-ODMT cEt N-Bz A Phosphoramidite (amidite) | 1197033-19-4 | >98.5% | 899.97 | 25 MG
SDP

Supplier:  Medchemexpress LLC 25MGHY148503

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This nucleoside phosphoramidite monomer is used for synthesizing locked nucleic acid (LNA) analog oligonucleotides, acting as a building block for antisense oligonucleotides (ASOs) to target complementary RNA sequences. Its 2',4'-constrained ethyl (cEt) modification enhances hybridization affinity and mismatch discrimination with RNA, improving oligonucleotides' resistance to exonuclease digestion and enabling gene expression regulation.

  • Synthesizes locked nucleic acid (LNA) analog oligonucleotides.
  • Enhances RNA hybridization affinity and mismatch discrimination.
  • Improves oligonucleotide resistance to exonuclease digestion.
  • Facilitates RNase H-dependent mRNA degradation.
  • Used in antisense drug development and gene research.
  • Improves qPCR probe/primer stability and melting temperature.

Catalog No. 50-003-63879


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