Learn More
Medchemexpress LLC 5'-ODMT cEt N-Bz A Phosphoramidite (amidite) | 1197033-19-4 | >98.5% | 899.97 | 25 MG

Supplier: Medchemexpress LLC 25MGHY148503
This nucleoside phosphoramidite monomer is used for synthesizing locked nucleic acid (LNA) analog oligonucleotides, acting as a building block for antisense oligonucleotides (ASOs) to target complementary RNA sequences. Its 2',4'-constrained ethyl (cEt) modification enhances hybridization affinity and mismatch discrimination with RNA, improving oligonucleotides' resistance to exonuclease digestion and enabling gene expression regulation.
- Synthesizes locked nucleic acid (LNA) analog oligonucleotides.
- Enhances RNA hybridization affinity and mismatch discrimination.
- Improves oligonucleotide resistance to exonuclease digestion.
- Facilitates RNase H-dependent mRNA degradation.
- Used in antisense drug development and gene research.
- Improves qPCR probe/primer stability and melting temperature.
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.