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Medchemexpress LLC Dimethylamino Parthenolide | 791595-09-0 | 98.0% | 293.40 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY16172100MG

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DMAPT (Dimethylamino Parthenolide) is an analogue of Parthenolide (PTL) and an orally active NF-κB inhibitor. It has an LD50 of 1.7 μM for cell population in AML cells and demonstrates potential anti-cancer and anti-metastatic effects. This product is for research use only.

  • Decreases constitutive NF-κB binding activity
  • Inhibits cell proliferation and viability in PC-3 and DU145 cells
  • Increases sensitivity of PC-3 tumor xenografts to X-rays
  • Slows normal tumor development in TRAMP mice
  • Reduces metastatic area in lung tissues in TRAMP mice

Catalog No. 50-003-92614


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