Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC VTP50469 fumarate | 2169919-29-1 | 99.8% | 804.93 | 1 ML
Supplier: Medchemexpress LLC HY114162A10MM/1ML
VTP50469 fumarate is a highly selective and orally active Menin-MLL interaction inhibitor. It demonstrates potent anti-leukemia activity by targeting MLL-rearranged and NPM1-mutant leukemia. This compound is intended for research use only.
- Potently inhibits Menin-MLL interaction with a Ki of 104 pM.
- Inhibits cell proliferation in MLL-rearranged and ALL cell lines.
- Induces apoptosis in MLL-r B cell ALL cell lines.
- Promotes differentiation in MLL-r AML cell lines.
- Displaces Menin from protein complexes.
- Effective in in vivo models of leukemia, improving survival.
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?