ACROBiosystems Recombinant Protein;Human PCSK9 (D374Y) Protein;HEK293;50UG;PCY,PCSK9,PCSK-9,FH3,HCHOLA3,LDLCQ1,NARC-1,NARC1,PC9
Manufacturer: ACROBiosystems PCYH522550UG
Recombinant Protein;Human PCSK9 (D374Y) Protein;50UG;Human PCSK9 (D374Y) Protein, Gln 31 - Gln 692 (D374Y) (Accession # AAI166619.1), was produced in human 293 cells (HEK293) at ACROBiosystems.;Human PCSK9 (D374Y) Protein is fused with a polyhistidine tag at the C-terminus, and has a calculated MW of 72 kDa. The predicted N-terminus is Gln 31. The reducing (R) protein migrates as 18 kDa and 65 kDa in SDS-PAGE due to glycosylation and proteolytic digestion.The D374Y mutation results in higher affinity of PCSK9 for LDLR.;Immobilized Human LDL R, His Tag (Cat. No. LDR-H5224) at 10 μg/mL (100 μl/well) can bind Human PCSK9 (D374Y), His Tag (Cat. No. PCY-H5225 ) with a linear range of 5-50 ng/mL (QC tested).
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