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Medchemexpress LLC 6,7-dihydro-8-(1-hydroxyethyl)-2-(pyridin-4-yl)-5H-pyrrolo[3,4-d]pyrimidin-4-amine, GP-82996, CINK4 | 359886-84-3 | 98.1% | 456.58 g/mol | C27H32N6O | 5 MG
SDP

Supplier:  Medchemexpress LLC HY1367265MG

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CGP-82996 is a small-molecule inhibitor of cyclin-dependent kinases CDK4 and CDK6 used in cellular and biochemical cancer research. It demonstrates inhibitory activity against CDK4/6 and can induce apoptosis in certain tumor cell lines (for example, U2OS).

  • Targets CDK4 and CDK6 with reported IC50s of 1.5 μM (CDK4/cyclin D1) and 5.6 μM (CDK6/cyclin D1).
  • Also shows activity against Cdk5/p35 (IC50 ≈ 25 μM).
  • High purity (98.1%) suitable for research applications.
  • Molecular formula C27H32N6O; molecular weight 456.58 g/mol.
  • Soluble in DMSO and intended for in vitro research use.

Catalog No. 50-002-21791


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