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Apexbio Technology LLC 6-Aminonicotinamide 329-89-5 500mg
Supplier: Apexbio Technology LLC C4497500
6-Aminonicotinamide is a small-molecule inhibitor targeting 6-phosphogluconate dehydrogenase (6-PGDH) a key enzyme of the pentose phosphate pathway It is designed to inhibit 6-PGDH activity thereby modulating cellular metabolism and the pentose phosphate pathway 6-Aminonicotinamide exerts its biological activity primarily by metabolic conversion to 6-amino-NAD(P ) competitively interfering with NAD(P )-dependent enzymatic reactions In in vitro studies 6-aminonicotinamide induces accumulation of 6-phosphogluconate demonstrating its inhibitory activity Based on these pharmacological properties 6-aminonicotinamide holds research potential in studies of cellular metabolism and the pentose phosphate pathway using cell culture systems and animal models
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