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ABclonal Technology 647 anti-h Desmoglein 3/PVA
Supplier: ABclonal Technology A26591500T
This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes cell-cell junctions between epithelial myocardial and other cell types The encoded preproprotein is proteolytically processed to generate the mature glycoprotein This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18 The encoded protein has been identified as the autoantigen of the autoimmune blistering disease pemphigus vulgaris
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