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ABclonal Technology 647 anti-Human CD66a/CEACAM1
Supplier: ABclonal Technology A24384100T
This gene encodes a member of the carcinoembryonic antigen (CEA) gene family part of the immunoglobulin superfamily Located on chromosome 19 the CEA family includes cell adhesion molecules and pregnancy-specific glycoproteins with 11 pseudogenes in the cluster The encoded protein initially identified in liver bile ducts as biliary glycoprotein functions as a cell-cell adhesion molecule found on leukocytes epithelia and endothelia It mediates cell adhesion through both homophilic and heterophilic binding This protein plays roles in tissue differentiation angiogenesis apoptosis tumor suppression metastasis and immune response modulation Multiple transcript variants encoding different isoforms have been reported though the full-length nature of all variants remains undefined
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