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ABclonal Technology 647 Rabbit anti-Human CD89
Supplier: ABclonal Technology A23349500T
This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils monocytes macrophages and eosinophils where it mediates immunologic responses to pathogens It interacts with IgA-opsonized targets and triggers several immunologic defense processes including phagocytosis antibody-dependent cell-mediated cytotoxicity and stimulation of the release of inflammatory mediators Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene
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