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Cayman Chemical 6mthylsulfInylheyl IsoTHO 10mg
Supplier: Cayman Chemical 1963810 MG
An isothiocyanate with diverse biological activities; inhibits NO production in mouse peritoneal exudate macrophages at 5 µM; inhibits arachidonic acid-induced aggregation of isolated human platelets (IC50 = 21.9 µM); reduces cell survival in a panel of breast, brain, colon, lung, ovarian, renal, and prostate cancer cell lines (mean IC50 = 43.7 µM); reduces apoptosis of substantia nigral dopaminergic neurons and motor dysfunction in a mouse model of 6-OHDA-induced Parkinson's disease at 5 mg/kg twice weekly; reduces the number of lung metastases in a B16/F10 murine melanoma model
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