Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Apexbio Technology LLC 7,8-dihydro-L-Biopterin 6779-87-9 5mg
Supplier: Apexbio Technology LLC B78295
7 8-dihydro-L-Biopterin (CAS 6779-87-9) is a reduced pterin and a biochemical precursor of tetrahydrobiopterin (BH4) a critical cofactor in the regulation of endothelial nitric oxide synthase (eNOS) BH4 is essential for nitric oxide (NO) synthesis and its oxidation or depletion alters NO-dependent signaling and increases oxidative stress a phenomenon observed in vascular cells under diabetic conditions 7 8-dihydro-L-Biopterin noncompetitively inhibits rat liver GTP cyclohydrolase I with a reported Ki of 14 4 M demonstrating approximately 12-fold higher potency compared to oxidized pterins This compound is valuable for elucidating redox regulation in eNOS signaling and for investigating pterin-mediated modulation of vascular oxidative responses
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?