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Medchemexpress LLC 7-methoxy-4-((6-phenyl-1,2,4-triazolo[4,3-b]pyridazin-3-yl)methoxy)quinoline | 1002304-34-8 | 99.9% | 50 MG
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Supplier:  Medchemexpress LLC HY1203550MG

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AMG-208 is an orally active small-molecule inhibitor of c-Met and RON tyrosine kinases used in preclinical cancer research. It demonstrates low-nanomolar biochemical potency against c-Met, cellular activity in cancer cell lines, and reported CYP3A4 inhibition. Supplied for laboratory research use only.

  • Orally active c-Met and RON tyrosine kinase inhibitor
  • Biochemical IC50 for c-Met ≈ 9 nM
  • Cellular activity: inhibits c-Met autophosphorylation in prostate cancer cells (IC50 ≈ 46 nM)
  • Reports CYP3A4 inhibition (IC50 ≈ 32 μM)
  • High research-grade purity (≈99.9%)

Catalog No. 50-002-33296


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