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Apexbio Technology LLC 740 Y-P 1236188-16-1 5mg

Supplier: Apexbio Technology LLC B52465
740 Y-P (CAS number 1236188-16-1) is a cell-permeable activator of phosphoinositide 3-kinase (PI3K) PI3K is implicated in various fundamental cellular processes including vesicle transport glucose uptake migration and survival signaling Treatment of human melanoma MNT-1 cells with 740 Y-P at 20 M for 24 hours activates PI3K signaling leading to significant reduction of sucrose-induced vacuole formation In serum-free cultured cerebellar granule neurons 740 Y-P interacts with the regulatory subunit p85 of PI3K promoting Akt phosphorylation and thus enhancing cell survival This compound is commonly employed in scientific research to study PI3K/Akt-mediated mechanisms
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