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Apexbio Technology LLC 9-Phenanthrol 484-17-3 50mg
Supplier: Apexbio Technology LLC B772850
9-Phenanthrol (CAS 484-17-3) is a selective inhibitor of the human TRPM4 ion channel exhibiting an IC50 of approximately 20 M By specifically blocking TRPM4-mediated cation currents 9-Phenanthrol modulates calcium-dependent ionic fluxes in various cell types This compound is frequently utilized to investigate the role of TRPM4 in the regulation of ionic homeostasis and excitability in cardiomyocytes Its application enables studies on the involvement of TRPM4 in cardiac ischemia-reperfusion injury and facilitates the exploration of cardiac protective mechanisms at the cellular and molecular levels in cardiovascular research
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