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Apexbio Technology LLC A 350619 hydrochloride 1217201-17-6 10mg
Supplier: Apexbio Technology LLC B533610
A 350619 hydrochloride (CAS 1217201-17-6) is a small-molecule activator targeting soluble guanylyl cyclase (sGC) It is designed to activate sGC and modulate the nitric oxide (NO)-sGC-cGMP signaling pathway thereby regulating vascular smooth muscle relaxation neurotransmission platelet aggregation inhibition and immune system function A 350619 hydrochloride exerts its biological activity primarily by increasing the maximal velocity (Vmax) and reducing the substrate-binding affinity (Km) of sGC In vitro studies indicate this compound synergizes with YC-1 suggesting overlapping or common binding sites Based on these pharmacological properties A 350619 hydrochloride holds research potential in the study of cGMP-related pathophysiology including erectile dysfunction
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