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Apexbio Technology LLC Amyloid Beta-Peptide (1-40) (human) 131438-79-4 25mg
Supplier: Apexbio Technology LLC A112425
Amyloid Beta-Peptide (1-40) (human) (CAS 131438-79-4) is a synthetic peptide composed of 40 amino acids identical to residues 1-40 of human amyloid-beta (A ) characterized by molecular weight of 4329 8 Da Derived from amyloid precursor protein (APP) via sequential proteolytic cleavage by - and -secretases A peptides form extracellular plaques and vascular deposits commonly observed in Alzheimer s disease pathology A 40 is among the predominant isoforms generated primarily through cleavage in the transmembrane region of APP within the Golgi apparatus As a model peptide A (1-40) is widely employed to study amyloid fibril formation neurotoxicity mechanisms and therapeutic strategies targeting Alzheimer s disease progression
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