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Cayman Chemical a-methyl SerotonInmaleate 10mg
Supplier: Cayman Chemical 2854210 MG
A 5-HT receptor agonist; binds selectively to 5-HT1A, 5-HT1B, 5-HT1C, and 5-HT1D receptors over 5-HT1E receptors (Kis = 42, 85, 150, 150, and >10,000 nM, respectively); selective for 5-HT2B and 5-HT2C receptors over 5-HT2A receptors (EC50s = 2.98, 50.1, and 794 nM, respectively); potentiates NMDA-induced motor neuron depolarizations in the presence of the NMDA receptor antagonist memantine in R. pipiens (frog) spinal cord ex vivo at 30 μM; increases dopamine release from rat striatum in vivo in a dose-dependent manner; increases systolic blood pressure and transiently increases heart rate in conscious dogs at 64 μg/kg
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