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Cayman Chemical a-Thujon 10mg
Supplier: Cayman Chemical 3979210 MG
A monoterpene ketone with diverse biological activities; inhibits ACh-induced currents in Xenopus oocytes expressing human α7 nAChRs (IC50 = 27 µM); reduces GABA-induced current amplitude in HEK293 cells expressing α1β2δ subunit-containing GABA receptors at 100 and 300 µM; reduces levels of FCV-F9 and MNV-1 in a plaque formation assay at 25 mM; impairs nicotine-induced enhancement of long-term potentiation in the dentate gyrus in rats at 1.25 mg/kg, i.p.; inhibits lung metastasis and increases survival in a B16/F10 murine melanoma model at 1 mg/kg
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