Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000137799

ABclonal Technology BRCA1 Rabbit pAb
SDP

Supplier:  ABclonal Technology A0212500UL

Encompass_Preferred

This gene encodes a 190 kDa nuclear phosphoprotein that helps maintain genomic stability and functions as a tumor suppressor. It spans 22 exons over ~110 kb and forms part of the BRCA1-associated genome surveillance complex (BASC), interacting with DNA repair proteins and RNA polymerase II. Through its C-terminal domain, it also associates with histone deacetylase complexes, contributing to transcription regulation, DNA repair, and recombination. Mutations in BRCA1 account for ~40% of inherited breast cancers and over 80% of inherited breast and ovarian cancers. Alternative splicing affects its localization and function, with many transcript variants described, some linked to disease. A related pseudogene also exists on chromosome 17.

Catalog No. 50-001-37799


May include imposed supplier surcharges.
Only null left
Add to Cart

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.