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ABclonal Technology A0289-500ul MMP9
Supplier: ABclonal Technology A0289500UL
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes such as embryonic development reproduction and tissue remodeling as well as in disease processes such as arthritis and metastasis Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases The enzyme encoded by this gene degrades type IV and V collagens Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow and murine studies suggest a role in tumor-associated tissue remodeling
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