Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
ABclonal Technology PSMD1 Rabbit pAb
Supplier: ABclonal Technology A16420500UL
The 26S proteasome is a multicatalytic proteinase complex composed of a 20S core and a 19S regulator. The 20S core has 4 rings made of 28 subunits, including 7 alpha and 7 beta subunits in each ring. The 19S regulator consists of a base with 6 ATPase subunits and 2 non-ATPase subunits, and a lid with up to 10 non-ATPase subunits. Proteasomes, found throughout eukaryotic cells, cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. A modified form, the immunoproteasome, processes class I MHC peptides. This gene encodes the largest non-ATPase subunit of the 19S regulator lid, responsible for substrate recognition and binding. Evidence suggests interactions with viral proteins, including coronaviruses. Alternative splicing produces multiple transcript variants.
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?