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ABclonal Technology pan-Mono-MethylR（R*GG）Motif Rabbit pAb
Supplier: ABclonal Technology A182971000UL
Arginine methylation is a common posttranslational modification found on histone and non-histone proteins. Three types exist in mammalian cells: monomethylarginine (MMA), asymmetric dimethylarginine (ADMA), and symmetric dimethylarginine (SDMA). ADMA, the most prevalent, has two methyl groups on one nitrogen of the guanidino group. SDMA and MMA occur at 20-50% of ADMA levels, with SDMA having one methyl group on each nitrogen and MMA having a single methyl group. These modifications are found on various proteins in the cytoplasm, nucleus, and organelles of mammalian cells. Methylated arginine residues are often flanked by glycine residues, though there are many exceptions.
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