Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
ABclonal Technology Acetyl-alpha Tubulin -K40 Rabbit pAb
Supplier: ABclonal Technology A230691000UL
This gene encodes alpha tubulin, a key component of microtubules in eukaryotic cells. Microtubules, composed of alpha and beta tubulins, perform essential functions in the cytoskeleton. Tubulin genes are highly conserved and belong to the tubulin superfamily, with alpha, beta, and gamma tubulins present in all eukaryotes. Gamma tubulin is crucial for microtubule assembly nucleation. This alpha-tubulin gene is one of three in a cluster on chromosome 12q and shares similarity with mouse and rat Tuba1 genes. Its expression is mainly found in differentiated neurological cells. Mutations in this gene cause lissencephaly type 3 (LIS3), a neurological disorder with microcephaly, intellectual disability, and early-onset epilepsy due to impaired neuronal migration. Alternative splicing results in multiple isoforms.
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?